Changzhou Bole Tech Co.,Ltd
Granulation, a technique of particle enlargement by agglomeration, is one of the most significant unit operations in the production of pharmaceutical dosage forms, mostly tablets and capsules. During the granulation process, small fine or coarse particles are converted into large agglomerates called granules. Generally, granulation commences after initial dry mixing of the necessary powder ingredients along with the active pharmaceutical ingredient (API), so that a uniform distribution of each ingredient throughout the po
Recent process in wet granulation
Wet granulation is the widely used technique and the granules are produced by wet massing of the excipients and API with granulation liquid with or without binder. Wet granulation has witnessed various technical and technological innovations such as steam granulation, moisture-activated dry granulation or moist granulation, thermal adhesion granulation, melt granulation, freeze granulation, foamed binder or foam granulation, and reverse wet granulation.
Dry granulation in pharmaceutical industry
Application: In case of low bulk densities, bad flowing properties and the risk of segregation of the mixture tableting machines have problems to press high quality tablets which are required in the Pharmaceutical Industry. To press these mixtures a granulation technology is required to change the material behavior to god flowing, higher bulk density and reduce the tendency of segregation.
Advantages and disadvantages of dry granulation process
Roller compactor is also know as dry granulator, it is one of the most important granulating machines in the granulation process. Today we will discuss the advantages and disadvantages of dry granulation process.
If you're involved in the process manufacturing, there is a granulating machine you need to be familiar with - Dry Granulator (Or called roller compactor).
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